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Signs and Symptoms, CausesSigns and Symptoms The most common symptoms of pleural effusion are shortness of breath and chest pain caused by compression of the lungs. Cough also can occur and there may be fever with empyema. Causes Common causes of pleural effusion are cardiac failure, tuberculosis, pulmonary embolism (blocked pulmonary artery), metastatic disease (cancer that has spread to the pleurae), lymphoma (cancer in lymphoid tissue), and trauma. Less common causes are liver and kidney disease...Read the full article
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